Genetic drift and mutational hazard in the evolution of salamander genomic gigantism.

doi:10.1111/evo.13084

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Article

Genetic drift and mutational hazard in the evolution of salamander genomic gigantism.

Evolution; international journal of organic evolution - 1 Dec 2016

Mohlhenrich Erik Roger, Mueller Rachel Lockridge

Abstract excerpt

Salamanders have the largest nuclear genomes among tetrapods and, excepting lungfishes, among vertebrates as a whole. Lynch and Conery (2003) have proposed the mutational-hazard hypothesis to explain variation in genome size and complexity. Under this hypothesis, noncoding DNA imposes a selective cost by increasing the target for degenerative mutations (i.e., the mutational hazard). Expansion of noncoding DNA,...

Topics

Animals
Anura
Biological Evolution
Evolution, Molecular
Genetic Drift
Genome Size
Mutation
Sequence Analysis, DNA
Caudata

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Open in PubMed

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PMID: 27714793
DOI: 10.1111/evo.13084

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