Article
Structural Mutations Set an Equilibrium Noncoding Genome Fraction.
Molecular biology and evolution - 28 Nov 2025
Luiselli Juliette, Banse Paul, Mazet Olivier, Lartillot Nicolas, Beslon Guillaume
Abstract excerpt
The evolution of noncoding genome size remains poorly understood. While part of noncoding DNA arguably plays a regulatory role, a significant portion does not appear to have a detectable phenotypic effect. The abundance of nonfunctional DNA in genomes, observed across the Tree of Life, challenges purely adaptationist explanations. Several nonadaptive theories have been proposed to explain its presence and...
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