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Article

Attenuated <i>Bordetella pertussis</i> Protects against Highly Pathogenic Influenza A Viruses by Dampening the Cytokine Storm

6 May 2010

Abstract excerpt

The threat of a pandemic spread of highly virulent influenza A viruses currently represents a top global public health problem. Mass vaccination remains the most effective way to combat influenza virus. However, current vaccination strategies face the challenge to meet the demands in a pandemic situation. In a mouse model of severe influenza virus-induced pneumonitis, we observed that prior nasal administration...

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PMID: 20444902
DOI: 10.1128/jvi.02542-09

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