Article
Telomerase RNA Component Genetic Variants Interact With the Mediterranean Diet Modifying the Inflammatory Status and its Relationship With Aging: CORDIOPREV Study.
The journals of gerontology. Series A, Biological sciences and medical sciences - 2 Mar 2018
Gomez-Delgado Francisco, Delgado-Lista Javier, Lopez-Moreno Javier, Rangel-Zuñiga Oriol Alberto, Alcala-Diaz Juan Francisco, Leon-Acuña Ana, Corina Andreea, Yubero-Serrano Elena, Torres-Peña Jose David, Camargo Antonio, Garcia-Rios Antonio, Caballero Javier, Castaño Justo, Ordovas Jose M, Lopez-Miranda Jose, Perez-Martinez Pablo
Abstract excerpt
Background: Leukocyte telomere length (LTL) attrition has been associated with age-related diseases. Telomerase RNA Component (TERC) genetic variants have been associated with LTL; whereas fatty acids (FAs) can interact with genetic factors and influence in aging. We explore whether variability at the TERC gene locus interacts with FA profile and two healthy diets (low-fat diet vs Mediterranean diet [MedDiet])...
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