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Article

Sequence variation in telomerase reverse transcriptase (TERT) as a determinant of risk of cardiovascular disease: the Atherosclerosis Risk in Communities (ARIC) study.

BMC medical genetics - 23 Jul 2015

Bressler Jan, Franceschini Nora, Demerath Ellen W, Mosley Thomas H, Folsom Aaron R, Boerwinkle Eric

Abstract excerpt

BACKGROUND: Telomerase reverse transcriptase (TERT) maintains telomere ends during DNA replication by catalyzing the addition of short telomere repeats. The expression of telomerase is normally repressed in somatic cells leading to a gradual shortening of telomeres and cellular senescence with aging. Interindividual variation in leukocyte telomere length has been previously associated with susceptibility to...

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Source

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Identifiers

PMID: 26201603
DOI: 10.1186/s12881-015-0194-x
PMCID: PMC4557920

Genes

TERT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Sequence variation in telomerase reverse transcriptase (TERT) as a determinant of risk of cardiovascular disease: the Atherosclerosis Risk in Communities (ARIC) study.PMID 26201603Read ↗

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