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Article

Association of TERC and OBFC1 haplotypes with mean leukocyte telomere length and risk for coronary heart disease.

PloS one - 1 Jan 2013

Maubaret Cécilia G, Salpea Klelia D, Romanoski Casey E, Folkersen Lasse, Cooper Jackie A, Stephanou Coralea, Li Ka Wah, Palmen Jutta, Hamsten Anders, Neil Andrew, Stephens Jeffrey W, Lusis Aldons J, Eriksson Per, Talmud Philippa J, Humphries Steve E

Abstract excerpt

OBJECTIVE: To replicate the associations of leukocyte telomere length (LTL) with variants at four loci and to investigate their associations with coronary heart disease (CHD) and type II diabetes (T2D), in order to examine possible causal effects of telomere maintenance machinery on disease aetiology. METHODS: Four SNPs at three loci BICD1 (rs2630578 GγC), 18q12.2 (rs2162440 GγT), and OBFC1 (rs10786775 CγG,...

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Share to Coronary Disease
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Source

Open in PubMed Open full text

Identifiers

PMID: 24349443
DOI: 10.1371/journal.pone.0083122
PMCID: PMC3861448

Genes

BICD1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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