Article
Polymorphism at the TNF-alpha gene interacts with Mediterranean diet to influence triglyceride metabolism and inflammation status in metabolic syndrome patients: From the CORDIOPREV clinical trial.
Molecular nutrition & food research - 1 Jul 2014
Gomez-Delgado Francisco, Alcala-Diaz Juan Francisco, Garcia-Rios Antonio, Delgado-Lista Javier, Ortiz-Morales Ana, Rangel-Zuñiga Oriol, Tinahones Francisco Jose, Gonzalez-Guardia Lorena, Malagon Maria M, Bellido-Muñoz Enrique, Ordovas Jose M, Perez-Jimenez Francisco, Lopez-Miranda Jose, Perez-Martinez Pablo
Abstract excerpt
SCOPE: To examine whether the consumption of a Mediterranean diet (MedDiet), compared with a low-fat diet, interacts with two single nucleotide polymorphisms at the tumor necrosis factor alpha gene (rs1800629, rs1799964) in order to improve triglycerides (TG), glycemic control, and inflammation markers. METHODS AND RESULTS: Genotyping, biochemical measurements, dietary intervention, and oral fat load test meal...
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