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Article

Copy number gain of VCX, X-linked multi-copy gene, leads to cell proliferation and apoptosis during spermatogenesis.

Oncotarget - 29 Nov 2016

Ji Juan, Qin Yufeng, Wang Rong, Huang Zhenyao, Zhang Yan, Zhou Ran, Song Ling, Ling Xiufeng, Hu Zhibin, Miao Dengshun, Shen Hongbing, Xia Yankai, Wang Xinru, Lu Chuncheng

Abstract excerpt

Male factor infertility affects one-sixth of couples worldwide, and non-obstructive azoospermia (NOA) is one of the most severe forms. In recent years there has been increasing evidence to implicate the participation of X chromosome in the process of spermatogenesis. To uncover the roles of X-linked multi-copy genes in spermatogenesis, we performed systematic analysis of X-linked gene copy number variations...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 27705943
DOI: 10.18632/oncotarget.12397
PMCID: PMC5340235

Genes

VCX
NXF2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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