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Article

ESX1 gene as a potential candidate responsible for male infertility in nonobstructive azoospermia.

Scientific reports - 2 Oct 2023

Malcher Agnieszka, Graczyk Zuzanna, Bauer Hermann, Stokowy Tomasz, Berman Andrea, Smolibowski Mikołaj, Blaszczyk Dominika, Jedrzejczak Piotr, Yatsenko Alexander N, Kurpisz Maciej

Abstract excerpt

Infertility is a problem that affects approximately 15% of couples, and male infertility is responsible for 40-50% of these cases. The cause of male infertility is still poorly diagnosed and treated. One of the prominent causes of male infertility is disturbed spermatogenesis, which can lead to nonobstructive azoospermia (NOA). Whole-genome sequencing (WGS) allows us to identify novel rare variants in potentially...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 37783880
DOI: 10.1038/s41598-023-43854-9
PMCID: PMC10545701

Genes

ESX1
CCND1
CXCR4
NANOG
PDE1C
RPS6KA5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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