Article
Bone Shaft Revascularization After Marrow Ablation Is Dramatically Accelerated in BSP-/- Mice, Along With Faster Hematopoietic Recolonization.
Journal of cellular physiology - 1 Sept 2017
Bouleftour Wafa, Granito Renata Neves, Vanden-Bossche Arnaud, Sabido Odile, Roche Bernard, Thomas Mireille, Linossier Marie Thérèse, Aubin Jane E, Lafage-Proust Marie-Hélène, Vico Laurence, Malaval Luc
Abstract excerpt
The bone organ integrates the activity of bone tissue, bone marrow, and blood vessels and the factors ensuring this coordination remain ill defined. Bone sialoprotein (BSP) is with osteopontin (OPN) a member of the small integrin binding ligand N-linked glycoprotein (SIBLING) family, involved in bone formation, hematopoiesis and angiogenesis. In rodents, bone marrow ablation induces a rapid formation of medullary...
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