Article
Risk Prediction for Epithelial Ovarian Cancer in 11 United States-Based Case-Control Studies: Incorporation of Epidemiologic Risk Factors and 17 Confirmed Genetic Loci.
American journal of epidemiology - 15 Oct 2016
Clyde Merlise A, Palmieri Weber Rachel, Iversen Edwin S, Poole Elizabeth M, Doherty Jennifer A, Goodman Marc T, Ness Roberta B, Risch Harvey A, Rossing Mary Anne, Terry Kathryn L, Wentzensen Nicolas, Whittemore Alice S, Anton-Culver Hoda, Bandera Elisa V, Berchuck Andrew, Carney Michael E, Cramer Daniel W, Cunningham Julie M, Cushing-Haugen Kara L, Edwards Robert P, Fridley Brooke L, Goode Ellen L, Lurie Galina, McGuire Valerie, Modugno Francesmary, Moysich Kirsten B, Olson Sara H, Pearce Celeste Leigh, Pike Malcolm C, Rothstein Joseph H, Sellers Thomas A, Sieh Weiva, Stram Daniel, Thompson Pamela J, Vierkant Robert A, Wicklund Kristine G, Wu Anna H, Ziogas Argyrios, Tworoger Shelley S, Schildkraut Joellen M
Abstract excerpt
Previously developed models for predicting absolute risk of invasive epithelial ovarian cancer have included a limited number of risk factors and have had low discriminatory power (area under the receiver operating characteristic curve (AUC) < 0.60). Because of this, we developed and internally validated a relative risk prediction model that incorporates 17 established epidemiologic risk factors and 17...
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