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Article

Appraising the role of previously reported risk factors in epithelial ovarian cancer risk: A Mendelian randomization analysis

7 Aug 2019

Abstract excerpt

BACKGROUND: Various risk factors have been associated with epithelial ovarian cancer risk in observational epidemiological studies. However, the causal nature of the risk factors reported, and thus their suitability as effective intervention targets, is unclear given the susceptibility of conventional observational designs to residual confounding and reverse causation. Mendelian randomization (MR) uses genetic...

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PMID: 31390370
DOI: 10.1371/journal.pmed.1002893

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