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Identifying novel tumor-related antigens and immune phenotypes for developing mRNA vaccines in lung adenocarcinoma.

International immunopharmacology - 1 Aug 2022

Zhou Bolun, Zang Ruochuan, Zhang Moyan, Song Peng, Liu Lei, Bie Fenglong, Peng Yue, Bai Guangyu, Gao Shugeng

Abstract excerpt

The mRNA vaccines have been a novel strategy of immunotherapies for multiple cancers. Although several types of mRNA vaccines have been investigated and validated in some studies, their efficacy among patients with lung adenocarcinoma (LUAD) remains largely unknown. The number of tumor-associated antigens is not enough and no study focuses on stratifying the subgroup of LUAD patients suitable for vaccination....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 35504200
DOI: 10.1016/j.intimp.2022.108816

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