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Article

The C-terminal domain of connexin43 modulates cartilage structure via chondrocyte phenotypic changes.

Oncotarget - 8 Nov 2016

Gago-Fuentes Raquel, Bechberger John F, Varela-Eirin Marta, Varela-Vazquez Adrian, Acea Benigno, Fonseca Eduardo, Naus Christian C, Mayan Maria D

Abstract excerpt

Chondrocytes in cartilage and bone cells population express connexin43 (Cx43) and gap junction intercellular communication (GJIC) is essential to synchronize cells for coordinated electrical, mechanical, metabolic and chemical communication in both tissues. Reduced Cx43 connectivity decreases chondrocyte differentiation and defective Cx43 causes skeletal defects. The carboxy terminal domain (CTD) of Cx43 is...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 27682878
DOI: 10.18632/oncotarget.12197
PMCID: PMC5341963

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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