Article
Diverse functions of vertebrate gap junctions.
Trends in cell biology - 1 Dec 1998
Simon A M, Goodenough D A
Abstract excerpt
Gap junctions are clusters of intercellular channels between adjacent cells. The channels are formed by the direct apposition of oligomeric transmembrane proteins, permitting the direct exchange of ions and small molecules (< 1 kDa) between cells without involvement of the extracellular space. Vertebrate gap junction channels are composed of oligomers of connexins, an enlarging family of proteins consisting of...
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