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Article

Reovirus μ1 Protein Affects Infectivity by Altering Virus-Receptor Interactions

29 Sept 2016

Abstract excerpt

Proteins that form the reovirus outer capsid play an active role in the entry of reovirus into host cells. Among these, the σ1 protein mediates attachment of reovirus particles to host cells via interaction with cell surface glycans or the proteinaceous receptor junctional adhesion molecule A (JAM-A). The μ1 protein functions to penetrate the host cell membrane to allow delivery of the genome-containing viral...

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PMID: 27681135
DOI: 10.1128/jvi.01843-16

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