Development Refractoriness of MLL-Rearranged Human B Cell Acute Leukemias to Reprogramming into Pluripotency.

doi:10.1016/j.stemcr.2016.08.013

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Development Refractoriness of MLL-Rearranged Human B Cell Acute Leukemias to Reprogramming into Pluripotency.

Stem cell reports - 11 Oct 2016

Muñoz-López Alvaro, Romero-Moya Damià, Prieto Cristina, Ramos-Mejía Verónica, Agraz-Doblas Antonio, Varela Ignacio, Buschbeck Marcus, Palau Anna, Carvajal-Vergara Xonia, Giorgetti Alessandra, Ford Anthony, Lako Majlinda, Granada Isabel, Ruiz-Xivillé Neus, Rodríguez-Perales Sandra, Torres-Ruíz Raul, Stam Ronald W, Fuster Jose Luis, Fraga Mario F, Nakanishi Mahito, Cazzaniga Gianni, Bardini Michela, Cobo Isabel, Bayon Gustavo F, Fernandez Agustin F, Bueno Clara, Menendez Pablo

Abstract excerpt

Induced pluripotent stem cells (iPSCs) are a powerful tool for disease modeling. They are routinely generated from healthy donors and patients from multiple cell types at different developmental stages. However, reprogramming leukemias is an extremely inefficient process. Few studies generated iPSCs from primary chronic myeloid leukemias, but iPSC generation from acute myeloid or lymphoid leukemias (ALL) has not...

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PMID: 27666791
DOI: 10.1016/j.stemcr.2016.08.013
PMCID: PMC5063541

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

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