Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

BCL-2 system analysis identifies high-risk colorectal cancer patients

23 Sept 2016

Abstract excerpt

OBJECTIVE: The mitochondrial apoptosis pathway is controlled by an interaction of multiple BCL-2 family proteins, and plays a key role in tumour progression and therapy responses. We assessed the prognostic potential of an experimentally validated, mathematical model of BCL-2 protein interactions (DR_MOMP) in patients with stage III colorectal cancer (CRC). DESIGN: Absolute protein levels of BCL-2 family proteins...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell death mechanisms and regulation
Share to Clusterin in disease pathology
Share to Heat shock proteins research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 27663504
DOI: 10.1136/gutjnl-2016-312287

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

BCL-2 system analysis identifies high-risk colorectal cancer patientsPMID 27663504Read ↗

Prediction of risk scores for colorectal cancer patients from the concentration of proteins involved in mitochondrial apoptotic pathwaySemantic proximity Read ↗

Navigating the interplay between BCL-2 family proteins, apoptosis, and autophagy in colorectal cancerSemantic proximity Read ↗

Analysis of apoptosis protein expression in early-stage colorectal cancer suggests opportunities for new prognostic biomarkers.Semantic proximity Read ↗

Identification of BCL-XL as highly active survival factor and promising therapeutic target in colorectal cancerSemantic proximity Read ↗

Bcl-xL is an oncogenic driver in colorectal cancer.Semantic proximity Read ↗

<i>Bcl-xL</i> as a poor prognostic biomarker and predictor of response to adjuvant chemotherapy specifically in <i>BRAF</i> -mutant stage II and III colon cancerSemantic proximity Read ↗

MCL1 nuclear translocation induces chemoresistance in colorectal carcinomaSemantic proximity Read ↗

Alterations of the interactome of Bcl-2 proteins in breast cancer at the transcriptional, mutational and structural level.Semantic proximity Read ↗

Raf Kinase Inhibitor Protein Expression in a Survival Analysis of Colorectal Cancer PatientsSemantic proximity Read ↗

Linking patient outcome to high throughput protein expression data identifies novel regulators of colorectal adenocarcinoma aggressivenessSemantic proximity Read ↗

Study of apoptosis-related interactions in colorectal cancer.Semantic proximity Read ↗

Bcl‐xL as prognostic marker and potential therapeutic target in cholangiocarcinomaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.