Article
Bovine leukocyte adhesion deficiency (BLAD): a review.
The Journal of veterinary medical science - 1 Dec 2004
Nagahata Hajime
Abstract excerpt
Bovine leukocyte adhesion deficiency (BLAD) in Holstein cattle is an autosomal recessive congenital disease characterized by recurrent bacterial infections, delayed wound healing and stunted growth, and is also associated with persistent marked neutrophilia. The molecular basis of BLAD is a single point mutation (adenine to guanine) at position 383 of the CD18 gene, which caused an aspartic acid to glycine...
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