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Article

Immunohistochemical detection of IDH1 mutation, p53, and internexin as prognostic factors of glial tumors.

Journal of neuro-oncology - 1 Jul 2012

Takano Shingo, Kato Yukinari, Yamamoto Tetsuya, Kaneko Mika Kato, Ishikawa Eiichi, Tsujimoto Yuta, Matsuda Masahide, Nakai Kei, Yanagiya Ryo, Morita Shunpei, Tsuboi Koji, Matsumura Akira

Abstract excerpt

Isocitrate dehydrogenase 1 (IDH1) mutations, which are early and frequent genetic alterations in astrocytomas, oligodendrogliomas, oligoastrocytomas, and secondary glioblastomas, are specific to arginine 132 (R132). Recently, we established monoclonal antibodies (mAbs) against IDH1 mutations: ant...

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Source

Identifiers

PMID: 22396072
DOI: 10.1007/s11060-012-0837-0

Genes

IDH1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22396072-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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