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Article

Transcription-associated mutation of lasR in Pseudomonas aeruginosa.

DNA repair - 1 Oct 2016

Wang Chao, McPherson John R, Zhang Lian-Hui, Rozen Steve, Sabapathy Kanaga

Abstract excerpt

Pseudomonas aeruginosa is an opportunistic pathogen which infects cystic fibrosis and cancer patients with compromised immune systems. LasR is a master regulator which controls the virulence of P. aeruginosa in response to bacterial cell-density and host signals. During infection, lasR is frequently mutated, conferring P. aeruginosa a growth advantage in hosts and enhances resistance to widely used antibiotics....

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Source

Identifiers

PMID: 27650847
DOI: 10.1016/j.dnarep.2016.09.001

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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