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Article

African Ancestry-Specific Alleles and Kidney Disease Risk in Hispanics/Latinos.

Journal of the American Society of Nephrology : JASN - 1 Mar 2017

Kramer Holly J, Stilp Adrienne M, Laurie Cathy C, Reiner Alex P, Lash James, Daviglus Martha L, Rosas Sylvia E, Ricardo Ana C, Tayo Bamidele O, Flessner Michael F, Kerr Kathleen F, Peralta Carmen, Durazo-Arvizu Ramon, Conomos Matt, Thornton Timothy, Rotter Jerome, Taylor Kent D, Cai Jainwen, Eckfeldt John, Chen Han, Papanicolau George, Franceschini Nora

Abstract excerpt

African ancestry alleles may contribute to CKD among Hispanics/Latinos, but whether associations differ by Hispanic/Latino background remains unknown. We examined the association of CKD measures with African ancestry-specific APOL1 alleles that were directly genotyped and sickle cell trait (hemoglobin subunit β gene [HBB] variant) on the basis of imputation in 12,226 adult Hispanics/Latinos grouped according to...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 27650483
DOI: 10.1681/ASN.2016030357
PMCID: PMC5328161

Genes

HBB
APOL1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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