Genome-wide association study of red blood cell traits in Hispanics/Latinos: The Hispanic Community Health Study/Study of Latinos.

doi:10.1371/journal.pgen.1006760

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Article

Genome-wide association study of red blood cell traits in Hispanics/Latinos: The Hispanic Community Health Study/Study of Latinos.

PLoS genetics - 1 Apr 2017

Hodonsky Chani J, Jain Deepti, Schick Ursula M, Morrison Jean V, Brown Lisa, McHugh Caitlin P, Schurmann Claudia, Chen Diane D, Liu Yong Mei, Auer Paul L, Laurie Cecilia A, Taylor Kent D, Browning Brian L, Li Yun, Papanicolaou George, Rotter Jerome I, Kurita Ryo, Nakamura Yukio, Browning Sharon R, Loos Ruth J F, North Kari E, Laurie Cathy C, Thornton Timothy A, Pankratz Nathan, Bauer Daniel E, Sofer Tamar, Reiner Alex P

Abstract excerpt

Prior GWAS have identified loci associated with red blood cell (RBC) traits in populations of European, African, and Asian ancestry. These studies have not included individuals with an Amerindian ancestral background, such as Hispanics/Latinos, nor evaluated the full spectrum of genomic variation beyond single nucleotide variants. Using a custom genotyping array enriched for Amerindian ancestral content and 1000...

Topics

Erythrocyte Count
Erythrocytes
Female
Genome-Wide Association Study
Hemoglobins
Hispanic or Latino
Homeodomain Proteins
Humans

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Male

Polymorphism, Single Nucleotide

Proteasome Endopeptidase Complex

RNA, Long Noncoding

Solute Carrier Family 12, Member 2

Tumor Suppressor Proteins

alpha-Globins

beta-Globins

Prospero-Related Homeobox 1 Protein

Source

Open in PubMed Open full text

Identifiers

PMID: 28453575
DOI: 10.1371/journal.pgen.1006760
PMCID: PMC5428979

Genes

PROX1
PSMB5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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