Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Ethnicity-dependent influence of innate immune genetic markers on morphine PCA requirements and adverse effects in postoperative pain.

Pain - 1 Nov 2016

Somogyi Andrew A, Sia Alex T, Tan Ene-Choo, Coller Janet K, Hutchinson Mark R, Barratt Daniel T

Abstract excerpt

Although several genetic factors have been associated with postsurgical morphine requirements, those involving the innate immune system and cytokines have not been well investigated. The aim of this study was to investigate the contribution of genetic variability in innate immune signalling pathways to variability in morphine dosage after elective caesarean section under spinal anaesthesia in 133 Indian, 230...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Catechol O-Methyltransferase
Share to Interleukin-1beta

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Morphine

Share to Narcotics

Share to Pain Measurement

Share to Pain, Postoperative

Share to Singapore

Share to Transforming Growth Factor beta1

Source

Identifiers

PMID: 27649267
DOI: 10.1097/j.pain.0000000000000661

Genes

COMT
OPRM1
TGFB1
TLR2
ABCB1
BDNF
CASP1
CRP
MYD88
TLR4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Ethnicity-dependent influence of innate immune genetic markers on morphine PCA requirements and adverse effects in postoperative pain.PMID 27649267Read ↗

Innate Immune and Neuronal Genetic Markers Are Highly Predictive of Postoperative Pain and Morphine Patient-Controlled Analgesia Requirements in Indian but Not Chinese or Malay Hysterectomy Patients.Semantic proximity Read ↗

Ethnicity and OPRM variant independently predict pain perception and patient-controlled analgesia usage for post-operative pain.Semantic proximity Read ↗

Genetics and genomics in postoperative pain and analgesia.Semantic proximity Read ↗

Innate Immune Signalling Genetics of Pain, Cognitive Dysfunction and Sickness Symptoms in Cancer Pain Patients Treated with Transdermal Fentanyl.Semantic proximity Read ↗

Patient genetic heterogeneities acting as indicators of post-operative pain and opioid requirement in orthopedic surgery: A systematic review.Semantic proximity Read ↗

Association of Genetic Variants with Postsurgical Pain: A Systematic Review and Meta-analyses.Semantic proximity Read ↗

Human Genetic Variability Contributes to Postoperative Morphine Consumption.Semantic proximity Read ↗

Pharmacokinetic and neuroimmune pharmacogenetic impacts on slow-release morphine cancer pain control and adverse effects.Semantic proximity Read ↗

Pharmacogenomics of opioids and perioperative pain management.Semantic proximity Read ↗

Effects of Single Nucleotide Polymorphisms on Surgical and Postsurgical Opioid Requirements: A Systematic Review and Meta-Analysis.Semantic proximity Read ↗

Role of genetic polymorphisms on opioid safety and efficacy in cancer pain: A systematic review and meta-analysis.Semantic proximity Read ↗

Influence of genetic variants of opioid-related genes on opioid-induced adverse effects in patients with lung cancer: A STROBE-compliant observational study.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.