Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association between Catechol-O-methyltransferase rs4680 (G>A) polymorphism and lung cancer risk.

Diagnostic pathology - 4 Oct 2014

Tan Xiang, Chen Mingwu

Abstract excerpt

BACKGROUND: The association between the Val158Met polymorphism in the catechol-O-methyltransferase (COMT) gene and lung cancer risk remains controversial and inconclusive. Therefore, the meta-analysis was performed to provide a quality reevaluation of the association between the COMT Val158Met polymorphism and the risk of lung cancer. METHODS: Two major public databases (Pubmed and Embase) and several Chinese...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Case-Control Studies
Share to Catechol O-Methyltransferase
Share to Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Lung Neoplasms

Share to Mutation, Missense

Share to Odds Ratio

Share to Polymorphism, Single Nucleotide

Share to Risk Factors

Source

Open in PubMed Open full text

Identifiers

PMID: 25280560
DOI: 10.1186/s13000-014-0192-x
PMCID: PMC4196007

Genes

COMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association between Catechol-O-methyltransferase rs4680 (G>A) polymorphism and lung cancer risk.PMID 25280560Read ↗

Impact of Catechol-O-Methyltransferase Val 158Met (rs4680) Polymorphism on Breast Cancer Susceptibility in Asian PopulationSemantic proximity Read ↗

Association of COMT Val158Met polymorphism and breast cancer risk: an updated meta-analysis.Semantic proximity Read ↗

Interaction Between Environmental Risk Factors and Catechol-O-Methyltransferase (COMT) and X-Ray Repair Cross-Complementing Protein 1 (XRCC1) Gene Polymorphisms in Risk of Lung Cancer Among Non-Smoking Chinese Women: A Case-Control Study.Semantic proximity Read ↗

Contribution of catechol-O-methyltransferase Val158Met polymorphism to endometrial cancer risk in postmenopausal women: a meta-analysis.Semantic proximity Read ↗

Association between polymorphisms in COMT, PLCH1, and CYP17A1, and non-small-cell lung cancer risk in Chinese nonsmokers.Semantic proximity Read ↗

Catechol-O-methyltransferase Val158Met polymorphism and breast cancer risk in Asian population.Semantic proximity Read ↗

Significant association of catechol-O-methyltransferase Val158Met polymorphism with bladder cancer instead of prostate and kidney cancer.Semantic proximity Read ↗

The l58Val/Met polymorphism of catechol-O-methyl transferase gene and prostate cancer risk: a meta-analysis.Semantic proximity Read ↗

Lack of association between catechol-O-methyltransferase Val108/158Met polymorphism and breast cancer risk: a meta-analysis of 25,627 cases and 34,222 controls.Semantic proximity Read ↗

Influence of CMTM8 polymorphisms on Lung Cancer Susceptibility in the Chinese Han PopulationSemantic proximity Read ↗

Quantitative assessment of the effect of MTHFR polymorphisms on the risk of lung carcinoma.Semantic proximity Read ↗

COMT Val158Met polymorphism and breast cancer risk: evidence from 26 case-control studies.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.