Article
Splice form-dependent regulation of axonal arbor complexity by FMRP.
Developmental neurobiology - 1 Jun 2017
Zimmer Stephanie E, Doll Steven G, Garcia A Denise R, Akins Michael R
Abstract excerpt
The autism-related protein Fragile X mental retardation protein (FMRP) is an RNA binding protein that plays important roles during both nervous system development and experience dependent plasticity. Alternative splicing of the Fmr1 locus gives rise to 12 different FMRP splice forms that differ in the functional and regulatory domains they contain as well as in their expression profile among brain regions and...
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