Article
PIDD Mediates Radiation-Induced Microglia Activation.
Radiation research - 1 Oct 2016
Yang Nong, Gao Xican, Qu Xiaofei, Zhang Ruiguang, Tong Fan, Cai Qian, Dong Jihua, Hu Yu, Wu Gang, Dong Xiaorong
Abstract excerpt
Radiation-induced brain injury (RIBI) is the most common adverse effect that occurs after cranial radiation therapy (CRT). We have previously reported that CRT-induced release of pro-inflammatory cytokines in brain tissues and inhibition of neurogenesis in the hippocampus might be caused by microglial activation and may play an important role in RIBI. In this study we examined the role of p53-induced protein with...
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