Article
ASXL1 and JAK2V617F gene mutation screening in Iranian patients with chronic myeloid leukemia.
Asia-Pacific journal of clinical oncology - 1 Apr 2017
Valikhani Amir, Poopak Behzad, Ferdowsi Shirin, Azizi Tabesh Ghasem, Ghaffari Seyed H, Saraf Kazeruoni Ehsan, Rezaei Negar, Farshchi Alireza, Amirizadeh Naser
Abstract excerpt
AIM: In recent years, a few cases of chronic myeloid leukemia (CML) have been reported with both BCR-ABL and JAK2V617F mutations. Moreover, mutations in the additional sex comb-like 1 (ASXL1) gene were recently shown in various myeloid malignancies.There were no previous studies investigating the incidence of the ASXL1 and JAK2V617F mutations in Iranian patients with CML. Consequently, this study focuses on the...
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