Article
[Frequency and clinical features of ASXL2 gene mutation in acute myeloid leukemia patients with AML1- ETO fusion gene positive].
Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi - 14 Aug 2016
Zhao J X, Chen X H, Li J L, Pan J, Tan Y H, Xu Z F, Ren F G, Zhang Y F, Xu J, Li M Q, Li J, Zhang N, Chang J M, Wang X J, Wang H W
Abstract excerpt
OBJECTIVE: To investigate frequency and clinical features of additional sex combs-like 2 (ASXL2) gene mutation in acute myeloid leukemia (AML) patients with AML1-ETO fusion gene and to analyze the relationship between ASXL2 gene mutation and c- kit gene mutation. METHODS: Mutation analysis of exon 11 and 12 of ASXL2 gene in 59 de novo AML patients was performed by using polymerase chain reaction (PCR) followed by...
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