Article
A single-nucleotide polymorphism in MMP9 is associated with decreased risk of steroid-induced osteonecrosis of the femoral head.
Oncotarget - 18 Oct 2016
Du Jieli, Liu Wanlin, Jin Tianbo, Zhao Zhenqun, Bai Rui, Xue Huiqin, Chen Junyu, Sun Mingqi, Zhang Xiyang, Wang Guoqiang, Wang Jianzhong
Abstract excerpt
Osteonecrosis of the femoral head (ONFH) is a common hip joint disease, and steroid-induced ONFH accounts for a large number of cases. Here, we examined eight previously-identified single-nucleotide polymorphisms (SNPs) in the MPP2 and MPP9 genes of 285 steroid-induced ONFH patients and 507 healthy controls from northern China to determine whether these SNPs were associated with the risk of developing...
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