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Article

MMP8 polymorphism is associated with susceptibility to osteonecrosis of the femoral head in a Chinese Han population.

Oncotarget - 28 Mar 2017

An Feimeng, Du Jieli, Cao Yuju, Shi Jianping, Guo Yongchang, Jin Tianbo, Li Jian, Chen Junyu, Li Ping, Dong Mei, Wang Guoqiang, Wang Jianzhong

Abstract excerpt

Osteonecrosis of the femoral head (ONFH) is an orthopedic refractory disease that adversely affects quality of life. Matrix metalloproteinase-8 (MMP-8) produced by the bone marrow has been implicated in the degradation of collagen during bone development. We assessed whether MMP8 polymorphisms are associated with ONFH. In a case-control study, using χ2 tests and genetic model analyses, we genotyped 5 MMP8...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 28423488
DOI: 10.18632/oncotarget.15371
PMCID: PMC5400606

Genes

MMP8

Provenance

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