Article
Candidate SNP Markers of Chronopathologies Are Predicted by a Significant Change in the Affinity of TATA-Binding Protein for Human Gene Promoters.
BioMed research international - 1 Jan 2016
Ponomarenko Petr, Rasskazov Dmitry, Suslov Valentin, Sharypova Ekaterina, Savinkova Ludmila, Podkolodnaya Olga, Podkolodny Nikolay L, Tverdokhleb Natalya N, Chadaeva Irina, Ponomarenko Mikhail, Kolchanov Nikolay
Abstract excerpt
Variations in human genome (e.g., single nucleotide polymorphisms, SNPs) may be associated with hereditary diseases, their complications, comorbidities, and drug responses. Using Web service SNP_TATA_Comparator presented in our previous paper, here we analyzed immediate surroundings of known SNP markers of diseases and identified several candidate SNP markers that can significantly change the affinity of...
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