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Article

Candidate SNP Markers Significantly Altering the Affinity of the TATA-Binding Protein for the Promoters of Human Genes Associated with Primary Open-Angle Glaucoma.

International journal of molecular sciences - 28 Nov 2024

Zolotareva Karina, Dotsenko Polina A, Podkolodnyy Nikolay, Ivanov Roman, Makarova Aelita-Luiza, Chadaeva Irina, Bogomolov Anton, Demenkov Pavel S, Ivanisenko Vladimir, Oshchepkov Dmitry, Ponomarenko Mikhail

Abstract excerpt

Primary open-angle glaucoma (POAG) is the most common form of glaucoma. This condition leads to optic nerve degeneration and eventually to blindness. Tobacco smoking, alcohol consumption, fast-food diets, obesity, heavy weight lifting, high-intensity physical exercises, and many other bad habits are lifestyle-related risk factors for POAG. By contrast, moderate-intensity aerobic exercise and the Mediterranean...

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Topics

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Share to Databases, Genetic
Share to Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Glaucoma, Open-Angle

Share to Polymorphism, Single Nucleotide

Share to Promoter Regions, Genetic

Share to TATA-Box Binding Protein

Source

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Identifiers

PMID: 39684516
DOI: 10.3390/ijms252312802
PMCID: PMC11641052

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