Article

Predictors of Failure on Second-line Antiretroviral Therapy with Protease Inhibitor Mutations in Uganda

2020-05-28

Abstract excerpt

<title>Abstract</title> <p>Introduction Failure on second-line antiretroviral therapy (ART) with protease inhibitor (PI) mutations is on the rise. However, there is a paucity of information on the factors associated with this observation in the context of low-income countries. Knowledge of underlying factors is key if we are to minimize the number of PLHIV switched to costly third-line ART. Our study investigated...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: e1ae6104-6395-50ca-b46f-0f55e3b6b305
DOI: 10.21203/rs.3.rs-30512/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Predictors of Failure on Second-line Antiretroviral Therapy with Protease Inhibitor Mutations in UgandaDOI 10.21203/rs.3.rs-30512/v1Read

Predictors of failure on second-line antiretroviral therapy with protease inhibitor mutations in Uganda.Semantic proximity Read

Pretreatment HIV drug resistance results in virological failure and accumulation of additional resistance mutations in Ugandan children.Semantic proximity Read

Prevalence and factors associated with drug resistance mutations among HIV - 1 patients failing to achieve virological suppression on second line treatment in Tanzania.Semantic proximity Read

Increasing Prevalence of HIV Pretreatment Drug Resistance in Women But Not Men in Rural Uganda During 2005-2013.Semantic proximity Read

Determinants of virological failure and antiretroviral drug resistance in Mozambique.Semantic proximity Read

Second-line HIV Treatment in Ugandan Children: Favorable Outcomes and No Protease Inhibitor Resistance.Semantic proximity Read

Factors Associated with the Development of Drug Resistance Mutations in HIV-1 Infected Children Failing Protease Inhibitor-Based Antiretroviral Therapy in South Africa.Semantic proximity Read

Empiric tuberculosis treatment and 12-month mortality among sputum GeneXpert-negative adults living with HIV in Uganda in the era of widespread Antiretroviral therapy: A prospective cohort studySemantic proximity Read

Prevalence of Pre-antiretroviral-Treatment Drug Resistance by Gender, Age, and Other Factors in HIV-Infected Individuals Initiating Therapy in Kenya, 2013-2014.Semantic proximity Read

HIV-1 Drug Resistance Among Ugandan Adults Attending an Urban Out-Patient Clinic.Semantic proximity Read

Short communication: high rates of thymidine analogue mutations and dual-class resistance among HIV-infected Ugandan children failing first-line antiretroviral therapy.Semantic proximity Read

Virological Outcomes of Second-line Protease Inhibitor-Based Treatment for Human Immunodeficiency Virus Type 1 in a High-Prevalence Rural South African Setting: A Competing-Risks Prospective Cohort Analysis.Semantic proximity Read