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Article

CDK1 phosphorylates WRN at collapsed replication forks

16 Sept 2016

Abstract excerpt

Regulation of end-processing is critical for accurate repair and to switch between homologous recombination (HR) and non-homologous end joining (NHEJ). End resection is a two-stage process but very little is known about regulation of the long-range resection, especially in humans. WRN participates in one of the two alternative long-range resection pathways mediated by DNA2 or EXO1. Here we demonstrate that...

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PMID: 27634057
DOI: 10.1038/ncomms12880

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