Article
ADRB2 gly16gly Genotype, Cardiac Output, and Cerebral Oxygenation in Patients Undergoing Anesthesia for Abdominal Aortic Aneurysm Surgery.
Anesthesia and analgesia - 1 Dec 2016
Staalsø Jonatan Myrup, Rokamp Kim Zillo, Olesen Niels D, Lonn Lars, Secher Niels H, Olsen Niels V, Mantoni Teit, Helgstrand Ulf, Nielsen Henning B
Abstract excerpt
BACKGROUND: Gly16arg polymorphism of the adrenergic β2-receptor is associated with the elevated cardiac output (Q) in healthy gly16-homozygotic subjects. We questioned whether this polymorphism also affects Q and regional cerebral oxygen saturation (SCO2) during anesthesia in vascular surgical patients. METHODS: One hundred sixty-eight patients (age 71 ± 6 years) admitted for elective surgery were included....
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