Article
Characterization of the Glycoprotein Stable Signal Peptide in Mediating Pichinde Virus Replication and Virulence.
Journal of virology - 15 Nov 2016
Shao Junjie, Liu Xiaoying, Ly Hinh, Liang Yuying
Abstract excerpt
Arenaviruses can cause lethal hemorrhagic fevers in humans with few preventative and therapeutic measures. The arenaviral glycoprotein stable signal peptide (SSP) is unique among signal peptides in that it is an integral component of the mature glycoprotein complex (GPC) and plays important roles not only in GPC expression and processing but also in the membrane fusion process during viral entry. Using the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
