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Article

Identification of the Fusion Peptide-Containing Region in Betacoronavirus Spike Glycoproteins.

Journal of virology - 15 Jun 2016

Ou Xiuyuan, Zheng Wangliang, Shan Yiwei, Mu Zhixia, Dominguez Samuel R, Holmes Kathryn V, Qian Zhaohui

Abstract excerpt

UNLABELLED: The fusion peptides (FP) play an essential role in fusion of viral envelope with cellular membranes. The location and properties of the FPs in the spike (S) glycoproteins of different coronaviruses (CoV) have not yet been determined. Through amino acid sequence analysis of S proteins of representative CoVs, we identified a common region as a possible FP (pFP) that shares the characteristics of FPs of...

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Source

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Identifiers

PMID: 27030273
DOI: 10.1128/JVI.00015-16
PMCID: PMC4886789

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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