Article
Lunch eating predicts weight-loss effectiveness in carriers of the common allele at PERILIPIN1: the ONTIME (Obesity, Nutrigenetics, Timing, Mediterranean) study.
The American journal of clinical nutrition - 1 Oct 2016
Garaulet Marta, Vera Beatriz, Bonnet-Rubio Gemma, Gómez-Abellán Purificación, Lee Yu-Chi, Ordovás José M
Abstract excerpt
BACKGROUND: We propose that eating lunch late impairs the mobilization of fat from adipose tissue, particularly in carriers of PERILIPIN1 (PLIN1) variants. OBJECTIVE: The aim was to test the hypothesis that PLIN1, a circadian lipid-stabilizing protein in the adipocyte, interacts with the timing of food intake to affect weight loss. DESIGN: A total of 1287 overweight and obese subjects [229 men and 1058 women;...
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