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Article

CLOCK gene is implicated in weight reduction in obese patients participating in a dietary programme based on the Mediterranean diet.

International journal of obesity (2005) - 1 Mar 2010

Garaulet M, Corbalán M D, Madrid J A, Morales E, Baraza J C, Lee Y C, Ordovas J M

Abstract excerpt

INTRODUCTION: The success of obesity therapy is dependent on the genetic background of the patient. Circadian Locomotor Output Cycles Kaput (CLOCK), one of the transcription factors from the positive limb of the molecular clock, is involved in metabolic alterations. OBJECTIVE: To investigate whether five candidate polymorphisms from CLOCK were associated with anthropometric, metabolic measures and weight loss in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Diet, Mediterranean

Share to Linkage Disequilibrium

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Source

Open in PubMed Open full text

Identifiers

PMID: 20065968
DOI: 10.1038/ijo.2009.255
PMCID: PMC4426985

Genes

CLOCK

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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CLOCK gene is implicated in weight reduction in obese patients participating in a dietary programme based on the Mediterranean diet.PMID 20065968Read ↗

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Beneficial effect of CLOCK gene polymorphism rs1801260 in combination with low-fat diet on insulin metabolism in the patients with metabolic syndrome.Semantic proximity Read ↗

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Polymorphism in the CLOCK gene may influence the effect of fat intake reduction on weight loss.Semantic proximity Read ↗

Association between CLOCK gene polymorphisms with circadian rhythm, chrononutrition, dietary intake, and metabolic parameters in adolescents.Semantic proximity Read ↗

Association Between CLOCK 3111 T/C Polymorphism with Ghrelin, GLP-1, Food Timing, Sleep and Chronotype in Overweight and Obese Iranian AdultsSemantic proximity Read ↗

CLOCK 3111 T/C SNP interacts with emotional eating behavior for weight-loss in a Mediterranean population.Semantic proximity Read ↗

Influence of CLOCK Gene Variants on Weight Response after Bariatric Surgery.Semantic proximity Read ↗

PERIOD2 variants are associated with abdominal obesity, psycho-behavioral factors, and attrition in the dietary treatment of obesity.Semantic proximity Read ↗

Lunch eating predicts weight-loss effectiveness in carriers of the common allele at PERILIPIN1: the ONTIME (Obesity, Nutrigenetics, Timing, Mediterranean) study.Semantic proximity Read ↗

Circadian rhythms, food timing and obesity.Semantic proximity Read ↗

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