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Article

Early meal timing attenuates high polygenic risk of obesity

20 Jul 2025

Abstract excerpt

Abstract Objective We examined whether meal timing is associated with long‐term weight‐loss maintenance and whether meal timing interacts with a genome‐wide polygenic score (PRS‐BMI) on body weight‐related outcomes. We then examined the interaction of meal timing with 97 BMI‐related single‐nucleotide polymorphisms on obesity outcome. Methods Participants (N = 1195, mean age 41.07 [SD 12.68] years, female 80.8%,...

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PMID: 40685562
DOI: 10.1002/oby.24319

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