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CRISPR ‐Cas9 technology and its application in haematological disorders

13 Sept 2016

Abstract excerpt

The recent advent of the Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)-CRISPR associated protein 9 (Cas9) system for precise genome editing has revolutionized methodologies in haematology and oncology studies. CRISPR-Cas9 technology can be used to remove and correct genes or mutations, and to introduce site-specific therapeutic genes in human cells. Inherited haematological disorders...

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PMID: 27619566
DOI: 10.1111/bjh.14297

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