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CRISPR RNA-Guided Gene Editing and its Clinical Research Applications in Hematology with Focus on Inherited Germline Predisposition to Hematologic Malignancies

2024-06-10

Abstract excerpt

Clustered regularly interspaced short palindromic repeats (CRISPR) based gene-editing has begun to transform the treatment landscape of genetic diseases. The history of the discovery of CRISPR/CRISPR-associated (Cas) proteins/single guide RNA (sgRNA)-based gene-editing since the first report of repetitive sequences of unknown significance in 1987 is fascinating, instructive, and inspiring for future advances. The...

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Literature Corpus work
30bcae0f-0bdc-5672-ae4b-0a07aeac2d88
DOI
10.20944/preprints202406.0537.v1
Open publication

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CRISPR RNA-Guided Gene Editing and its Clinical Research Applications in Hematology with Focus on Inherited Germline Predisposition to Hematologic MalignanciesDOI 10.20944/preprints202406.0537.v1
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