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Advances in therapeutic application of CRISPR-Cas9

26 Nov 2019

Abstract excerpt

Clustered regularly interspaced short palindromic repeats (CRISPR)-associated protein 9 (Cas9) is one of the most versatile and efficient gene editing technologies, which is derived from adaptive immune strategies for bacteria and archaea. With the remarkable development of programmable nuclease-based genome engineering these years, CRISPR-Cas9 system has developed quickly in recent 5 years and has been widely...

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PMID: 31769791
DOI: 10.1093/bfgp/elz031

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