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Harnessing the evolving CRISPR/Cas9 for precision oncology

8 Aug 2024

Abstract excerpt

The Clustered Regularly Interspaced Short Palindromic Repeat (CRISPR)/Cas9 system, a groundbreaking innovation in genetic engineering, has revolutionized our approach to surmounting complex diseases, culminating in CASGEVY™ approved for sickle cell anemia. Derived from a microbial immune defense mechanism, CRISPR/Cas9, characterized as precision, maneuverability and universality in gene editing, has been...

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PMID: 39118151
DOI: 10.1186/s12967-024-05570-4

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