Article
APOA5 genetic and epigenetic variability jointly regulate circulating triacylglycerol levels.
Clinical science (London, England : 1979) - 1 Nov 2016
Oliva Iris, Guardiola Montse, Vallvé Joan-Carles, Ibarretxe Daiana, Plana Núria, Masana Lluís, Monk David, Ribalta Josep
Abstract excerpt
Apolipoprotein A5 gene (APOA5) variability explains part of the individual's predisposition to hypertriacylglycerolaemia (HTG). Such predisposition has an inherited component (polymorphisms) and an acquired component regulated by the environment (epigenetic modifications). We hypothesize that the integrated analysis of both components will improve our capacity to estimate APOA5 contribution to HTG. We followed a...
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