Article
Association of PRKAA1 gene polymorphisms with chronic hepatitis B virus infection in Chinese Han population.
The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases - 1 Jan 2000
Yuan Jun, Zhang Yan, Yan Fu-Tang, Zheng Xiao
Abstract excerpt
OBJECTIVE: Studies have indicated that AMPK play critical roles in the regulation of innate immunity and inflammatory responses. However, the role of the polymorphisms of PRKAA1 gene in immune-response to infectious organisms remains unknown. To evaluate the potential role of PRKAA1/AMPKα1 in the immune-response to HBV, we conducted this case-control study. METHODS: We recruited 276 patients (145 men and 131...
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