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Article

GenToS: Use of Orthologous Gene Information to Prioritize Signals from Human GWAS.

PloS one - 1 Jan 2016

Hoppmann Anselm S, Schlosser Pascal, Backofen Rolf, Lausch Ekkehart, Köttgen Anna

Abstract excerpt

Genome-wide association studies (GWAS) evaluate associations between genetic variants and a trait or disease of interest free of prior biological hypotheses. GWAS require stringent correction for multiple testing, with genome-wide significance typically defined as association p-value <5*10-8. This study presents a new tool that uses external information about genes to prioritize SNP associations (GenToS). For a...

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Identifiers

PMID: 27612175
DOI: 10.1371/journal.pone.0162466
PMCID: PMC5017755

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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