Article
Genetic Association of PARP15 Polymorphisms with Clinical Outcome of Acute Myeloid Leukemia in a Korean Population.
Genetic testing and molecular biomarkers - 1 Nov 2016
Lee Min Kyung, Cheong Hyun Sub, Koh Youngil, Ahn Kwang-Sung, Yoon Sung-Soo, Shin Hyoung Doo
Abstract excerpt
AIMS: Some members of the poly ADP-ribose polymerase (PARP) protein family have been regarded as targets for the therapeutic inhibition of cancer. Among these PARP genes, poly ADP-ribose polymerase family, member 15 (PARP15) is a candidate gene for cancer development due to its ability to regulate gene transcription and its reported association with apoptosis. The current study investigated the possible...
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