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Expression of DR4, DR5, FAS, Caspase-8 and, DDIAS Genes in AML Patients

20 Mar 2023

Abstract excerpt

Background: Acute myeloid leukemia (AML) is the most common acute leukemia in adults and accompanies a worse survival. In this study, gene expression levels of 5 key players of apoptosis, including DR4, DR5, FAS, caspase 8, and DNA damage-induced apoptosis suppressor (DDIAS), have been evaluated in AML patients compared with controls, aiming to evaluate their possible role and prognostic impact. Methods: This...

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PMID: 37575689
DOI: 10.47176/mjiri.37.68

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